FIELD: medicine; pharmaceuticals.
SUBSTANCE: invention relates to a pharmaceutical composition of antibacterial action, comprising active substance 4-(3-ethoxy-4-hydroxybenzyl)-5-oxo-5,6-dihydro-4H-[1,3,4]-thiadiazin-2-(2,4-difluorophenyl)-carboxamide in a crystalline form with a particle size of less than 50 mcm in amount of 150 to 600 mg in the form of an oral solid dosage form with acceptable excipients. Invention also relates to use of said pharmaceutical composition for treating acute, recurrent and chronic infections, such as complicated urinary tract infections, pneumonia, chronic urogenital infections, acute and chronic intestinal localization infections, caused by antibiotic-resistant strains of Pseudomonas aeruginosa, Enterococcus spp., Chlamydia trachomatis, Salmonella spp.
EFFECT: technical result is obtaining a new pharmaceutical composition which can find application in medicine.
4 cl, 32 tbl, 14 ex, 9 dwg
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Authors
Dates
2020-11-24—Published
2020-03-20—Filed