FIELD: biotechnology.
SUBSTANCE: application of 4-(3-ethoxy-4-hydroxybenzyl)-5-oxo-5,6-dihydro-4H-[1,3,4]-thiadiazine-2-(2,4-difluorophenyl)-carboxamide for suppression of an infection caused by antibiotic-resistant strains of Pseudomonas aeruginosa in the living body, as well as a method of suppression of the infection caused by antibiotic-resistant strains of Pseudomonas aeruginosa when exposed to Pseudomonas aeruginosa strains with an effective amount of this compound.
EFFECT: implementation of the claimed prescription for infection of mice with the indicated clinical strains genotypes, regardless of the acquired resistance, the compound does not have a bactericidal effect on the intestinal microflora of animals and is low-toxic.
2 cl, 3 dwg, 25 tbl
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Authors
Dates
2017-07-07—Published
2016-10-10—Filed