FIELD: medicine.
SUBSTANCE: group of inventions relates to medicine. Disclosed is use of a compound of hexahydro-dibenzo[a,g]quinolizine of formula (I) for preparing a drug for treating and/or preventing benign prostatic hyperplasia; using the same compound as an inhibitor for treating benign prostatic hyperplasia, for antagonism on norepinephrine-induced urethral smoothing, for antagonism to a norepinephrine-induced contraction of the prostate smooth muscle, to obtain an inhibitor selectively binding to α1A-adrenergic receptor; non-therapeutic in vitro inhibition method α1A-adrenergic receptor; method of treating and/or preventing benign prostatic hyperplasia; pharmaceutical composition of the same purpose and a method for preparing the pharmaceutical composition.
EFFECT: technical result: connection DC037009 significantly increased diuresis and reduced frequency of urination; low probability of side effects, for example, on heart and seminal ejaculation function of seminal vesicles.
15 cl, 5 dwg, 7 tbl, 9 ex
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