HETEROCYCLIC COMPOUND USED AS A FGFR INHIBITOR Russian patent published in 2021 - IPC C07D213/84 C07D401/12 C07D413/14 C07D401/14 A61K31/444 A61K31/4545 A61K31/506 A61K31/5377 A61K31/496 A61P35/00 

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to a compound of formula I or a pharmaceutically acceptable salt thereof, compounds specified in 6 claims, having FGFR activity inhibitor properties, pharmaceutical compositions based thereon, use thereof in preparing a drug for treating or preventing diseases, as well as a method of treating or preventing diseases mediated by FGFR. In general formula (I), rings A and R, each independently, are selected from a group consisting of substituted or unsubstituted 6-member heteroaryl groups with 1 to 2 nitrogen atoms, and in the presence of substitution, A or R can be substituted with one or two substituents in any position, and such substitute is independently selected from a group consisting of halogen, cyano, C1-C8 alkyl, -C(O)R¹, -OR¹ and - NR²R³, wherein said alkyl group is optionally substituted with one substitute selected from a group consisting of -OR⁴; X is NR⁷; Y is -C(O)-; R¹, R², R³ and R⁴, each independently selected from a group consisting of hydrogen and C1-C8 alkyl; R⁷ is C1-C8 alkyl.

EFFECT: heterocyclic compound used as FGFR inhibitor.

12 cl, 26 ex