FIELD: chemistry.
SUBSTANCE: invention relates to a method for producing nanocapsules vitamin D3 in the medium Tween-80, at a weight ratio of core:shell 1:1, characterized in that successively in a beaker with heated purified water were added an oil concentrate of vitamin D3, 2-hydroxy-β-cyclodextrin, emulsion (pre-melted) wax and Tween-80, then the system is stirred using an ultrahomogenizer at rate of 2000 rpm for 5 minutes, further, a magnetic stirrer with heating (exposure time 5 minutes) is used, then the obtained nanoemulsion is filtered out, dried on a lyophilic drier and powder of nanocapsules is obtained.
EFFECT: technical result is a novel method of producing nanocapsules of vitamin D3 in a tween-80 medium, with a weight ratio of core to shell of 1:1.
1 cl, 3 ex, 3 dwg
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Authors
Dates
2021-02-12—Published
2020-03-23—Filed