FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology. Disclosed is a vaccine against COVID-19. The vaccine composition contains peptide immunogens having amino acid sequences (SEQ ID NO: 1), (SEQ ID NO: 2) and (SEQ ID NO: 3), and chimeric recombinant carrier protein MBP-6xHis-N_nCoV-2019 characterized by the sequence (SEQ ID NO: 4). Moreover, the peptide immunogens are covalently linked to the specified carrier protein.
EFFECT: vaccine composition with the use of peptide immunogens and a carrier protein, which carry the minimum necessary antigenic determinants for the formation of a specific immune response and induce protective immunity against COVID-19.
3 cl, 5 dwg, 4 tbl, 7 ex
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Authors
Dates
2021-02-20—Published
2020-12-09—Filed