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2 801 597

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(51)

IPC

C07K14/01(2006-01-01)

C12N15/34(2006-01-01)

C12N15/62(2006-01-01)

C12N15/63(2006-01-01)

(21) (22)

Application

2022120316, 2022-07-25

(24)

Start date

2022-07-25

(22)

Actual filing date

2022-07-25

(45)

Published

2023-08-11

(72)

Inventor

Okhrimenko Ivan StanislavovichZagriadskaia Iuliia AleksandrovnaMishin Aleksei ViktorovichBorshchevskii Valentin IvanovichShevchenko Marina Aleksandrovna

(73)

Holder

Federalnoe Gosudarstvennoe Avtonomnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniia Fiziko-Tekhnicheskii Institut Issledovatelskii Universitet)»

ARTIFICIAL GENETIC CONSTRUCT FOR THE HETEROLOGOUS EXPRESSION OF THE S-PROTEIN RECEPTOR-BINDING DOMAIN IN A FUSED POLYPEPTIDE CHAIN WITH A NUCLEOCAPSID PROTEIN Russian patent published in 2023 - IPC C07K14/01 C12N15/34 C12N15/62 C12N15/63

Abstract RU 2801597 C1

FIELD: genetic engineering and biotechnology.

SUBSTANCE: invention relates to a de novo genetic construct that provides heterologous expression of the S-protein receptor-binding domain in a fused polypeptide chain with a nucleocapsid protein.

EFFECT: invention can be used in the heterologous synthesis of the said chimeric protein in recombinant producer strains, as well as in obtaining its homogeneous preparation suitable for structural and biophysical studies.

1 cl, 4 dwg

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RU 2 801 597 C1

Authors

Okhrimenko Ivan Stanislavovich

Zagriadskaia Iuliia Aleksandrovna

Mishin Aleksei Viktorovich

Borshchevskii Valentin Ivanovich

Shevchenko Marina Aleksandrovna

Dates

2023-08-11—Published

2022-07-25—Filed