ARTIFICIAL GENETIC CONSTRUCT FOR THE HETEROLOGOUS EXPRESSION OF THE S-PROTEIN RECEPTOR-BINDING DOMAIN IN A FUSED POLYPEPTIDE CHAIN WITH A NUCLEOCAPSID PROTEIN Russian patent published in 2023 - IPC C07K14/01 C12N15/34 C12N15/62 C12N15/63 

Abstract RU 2801597 C1

FIELD: genetic engineering and biotechnology.

SUBSTANCE: invention relates to a de novo genetic construct that provides heterologous expression of the S-protein receptor-binding domain in a fused polypeptide chain with a nucleocapsid protein.

EFFECT: invention can be used in the heterologous synthesis of the said chimeric protein in recombinant producer strains, as well as in obtaining its homogeneous preparation suitable for structural and biophysical studies.

1 cl, 4 dwg

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RU 2 801 597 C1

Authors

Okhrimenko Ivan Stanislavovich

Zagriadskaia Iuliia Aleksandrovna

Mishin Aleksei Viktorovich

Borshchevskii Valentin Ivanovich

Shevchenko Marina Aleksandrovna

Dates

2023-08-11Published

2022-07-25Filed