COMPRESSED PHARMACEUTICAL PRODUCT Russian patent published in 2021 - IPC A61K9/20 A61K9/50 A61K31/192 A61K47/32 A61K47/34 A61K47/38 A61P29/00 

Abstract RU 2744270 C2

FIELD: medical industry.

SUBSTANCE: invention relates to the medical industry, in particular to a pressed pharmaceutical product and a method for the production thereof, and also to a method for masking the unpleasant taste of a pressed pharmaceutical product. The pressed pharmaceutical product comprises coated particles produced by applying a film from a methacrylic acid copolymer and ethylacrylate to core particles containing ibuprofen, polyvinylacetal diethylaminoacetate, crystalline cellulose and ethylacrylate-methylmethacrylate copolymerand partially washed polyvinyl alcohol, where the coated particles contain ibuprofen, diethylaminocetate polyvinylacetal, crystalline cellulose and copolymer ethylacetate-methylmethacrylate, partially washed polyvinyl alcohol and the copolymer of methacrylic acid and ethylacetate, taken in certain quantities. The method for producing the pressed pharmaceutical product described above and a method for masking the unpleasant taste of the pressed pharmaceutical product described above are carried out by producing the core particles by granulating the above-described particle components, the coated particles are then prepared by applying a film from the copolymer methacrylic acid and ethylacetylate to the core particles and then the coated particles are pressed.

EFFECT: compressed pharmaceutical product described above and the methods (variants) have a good effect of masking bitterness, irritation or the like from an acid drug, and are also capable of maintaining a good sensation when ingested, without reducing the masking action to unpleasant taste over time.

5 cl, 4 tbl, 4 ex

Similar patents RU2744270C2

Title Year Author Number
SOLID MEDICINAL FORM FOR ORAL ADMINISTRATION OF PHARMACEUTICALLY ACTIVE SUBSTANCES SHOWING UNFAVORABLE ORGANOLEPTIC PROPERTIES 1991
  • Luidzhi Dzhovanni Mapelli[It]
  • Marko Dzhuzeppe Raffaehle Markoni[It]
  • Marko Zema[It]
RU2085190C1
PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION WITH MASKED TASTE AND PREPARATION METHOD THEREOF 2012
  • Chan Khi Chal
  • Park San Khan
  • Kan Bok Khi
RU2583935C2
EXTENDED-RELEASE FORMULATION FOR REDUCING THE FREQUENCY OF URINATION AND METHOD OF USE THEREOF 2012
  • Dill Devid A.
RU2603471C2
PASTILLE DOZED FORM 2018
  • Maknalli, Dzherard, P.
  • Anderson, Oliver
  • Koll, Gregori
RU2771806C2
TASTE-MASKING PHARMACEUTICAL COMPOSITIONS 2005
  • Frants Shvarts
  • Irina Kozilek
RU2399370C2
LAYERS FOR MECHANICAL PROTECTION OF SOLID DOSAGE FORMS 2008
  • Soler Ransani Luis
  • Kasadeval' Pukhals Khemma
RU2500389C2
ANALGESIC, ANTIPYRETIC, ANTI-INFLAMMATORY PREPARATION AND METHOD FOR ITS PREPARING 2003
  • Kaminskaja M.I.
  • Vasil'Eva T.V.
  • Dmitrieva I.M.
  • Zaripova Z.I.
  • Predeina N.I.
  • Chumakova L.K.
  • Jakovlev G.Ju.
RU2254854C2
TABLET WITH ENTEROSOLUBLE COATING AND METHOD OF PREPARING 1998
  • Ullakh Ismat
  • Uilej Gehri Dzh.
RU2201217C2
PHARMACEUTICAL COMPOSITION FOR PERORAL INTRODUCTION IN FORM OF PARTICLES WITH CALCULATED TIME OF RELEASE AND QUICKLY DECOMPOSING TABLETS CONTAINING SAID COMPOSITION 2005
  • Josida Takajuki
  • Tasaki Khiroaki
  • Katsuma Masataka
  • Maeda Atsusi
RU2382637C2
IBUPROFENE CHEWING TABLET 2012
  • Jan Lehj
  • Jan Fan
  • Lju Dzhon Tszjannan'
RU2567050C2

RU 2 744 270 C2

Authors

Onuki, Yoichi

Osawa, Ryoichi

Dates

2021-03-04Published

2016-12-26Filed