NEW THROMBIN INHIBITORS Russian patent published in 2021 - IPC C07K14/81 C07K7/08 C12P21/02 A61K38/10 A61K38/57 A61P7/02 G01N33/68 

Abstract RU 2745847 C2

FIELD: biotechnology.

SUBSTANCE: present invention relates to the field of biotechnology, specifically to peptide inhibitors of thrombin, and can be used in medicine for prevention or treatment of a disease associated with thrombosis, as well as for detecting the accumulation of thrombin in a subject.

EFFECT: invention provides production of peptides that are able to bind to thrombin with a high level of specificity and inhibit its activity.

19 cl, 28 dwg, 7 tbl, 1 ex

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RU 2 745 847 C2

Authors

Iyer Janaki Krishnamoorthy

Koh Cho Yeow

Kini R. Manjunatha

Kazimirova Maria

Roller Ladislav

Dates

2021-04-01Published

2016-06-17Filed