FIELD: pharmaceutical industry.
SUBSTANCE: present invention relates to salts (E)-N,N-dimethyl-4-((2-((5-((Z)-4,4,4-trifluoro-1-(3-fluoro-1H-indazole-5-yl)-2-phenylbut-1-en-1-yl)pyridin-2-yl) oxy) ethyl) amino) but-2-enamide represented by formula I and acid selected from the group consisting of hydrobromic acid, maleic acid and mandelic acid as well as crystals of these salts. The invention also relates to a pharmaceutical composition having ERα inhibiting activity based on said salts or their crystals.
EFFECT: new compounds, their crystals and a pharmaceutical composition based on them that can be used in medicine for the treatment of breast cancer.
32 cl, 6 ex, 22 dwg
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