FIELD: biology.
SUBSTANCE: invention relates to biotechnology, particularly to an O-succinylhomoserine transferase mutant, a polynucleotide encoding this mutant, a microorganism containing the mutant and a method of synthesis of O-succinylhomoserine and L-methionine using the microorganism. Proposed is polypeptide with O-succinyl homoserine transferase activity comprising an amino acid substitution at position 313 in the amino acid sequence of SEQ ID NO: 1 with an amino acid other than leucine.
EFFECT: invention allows synthesizing L-methionine with a high degree of efficiency.
14 cl, 8 tbl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| NEW O-SUCCINYL HOMOSERINE TRANSFERASE MUTANT AND METHOD FOR SYNTHESIS OF O-SUCCINYL HOMOSERINE USING SAID MUTANT | 2018 |
|
RU2747494C1 |
| O-SUCCINYL HOMOSERINE-PRODUCING MICROORGANISM AND METHOD OF PRODUCING O-SUCCINYL HOMOSERINE USING THEREOF | 2015 |
|
RU2723183C2 |
| COMPOSITION FOR PREVENTION AND TREATMENT OF SKIN DISEASE CONTAINING SUBSTANCE SPECIFICALLY BINDING WITH VIMENTINE DERIVATIVE PEPTIDE | 2018 |
|
RU2751486C1 |
| NEW VERSIONS OF HYALURONIDASE WITH IMPROVED STABILITY AND THE PHARMACEUTICAL COMPOSITION CONTAINING THEM | 2021 |
|
RU2811464C2 |
| VARIANT OF GENUS YARROWIA AND METHOD OF PRODUCING FAT USING SAME | 2021 |
|
RU2817101C1 |
| NEW VARIANT OF L-TYROSINE-EXPORTING PROTEIN AND METHOD OF OBTAINING L-TYROSINE USING IT | 2021 |
|
RU2808831C1 |
| NEW VARIANT OF CITRATE SYNTHASE AND METHOD FOR OBTAINING L-AMINO ACIDS USING IT | 2022 |
|
RU2836733C1 |
| NEW VARIANT OF AN L-TRYPTOPHAN EXPORTING PROTEIN AND METHOD FOR PRODUCING L-TRYPTOPHAN WITH APPLICATION THEREOF | 2020 |
|
RU2763603C1 |
| PROGRAMMED CELL DEATH (PD-1) PROTEIN-1 ANTIBODIES AND USE THEREOF | 2017 |
|
RU2725950C1 |
| VARIANT OF ALDOLASE AROG AND METHOD OF PRODUCING BRANCHED-CHAIN AMINO ACID USING SAME | 2021 |
|
RU2826456C1 |
