METHODS AND COMPOSITIONS FOR MODULATING EXPRESSION OF APOLIPOPROTEIN (A) Russian patent published in 2021 - IPC C12N15/113 A61K48/00 A61P3/00 A61P9/00 

Abstract RU 2748495 C2

FIELD: biotechnology.

SUBSTANCE: present invention relates to the field of biotechnology, in particular to antisense compounds, and can be used in medicine. The invention makes it possible to obtain an antisense oligonucleotide that can specifically inhibit the expression of apolipoprotein (apo (a)).

EFFECT: invention may be applicable in the prevention or treatment of inflammatory, cardiovascular and/or metabolic diseases, disorders or other conditions associated with apo (a) or Lp (a).

24 cl, 13 ex, 65 tbl

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RU 2 748 495 C2

Authors

Crooke, Rosanne, M.

Graham, Mark, J.

Freier, Susan, M.

Dates

2021-05-26Published

2013-05-23Filed