FIELD: biotechnology.
SUBSTANCE: obtained modified antisense compounds are able to specifically inhibit the expression of the nucleic acid apo (a). The invention may be used as a medicament for treating, preventing or slowing the progression of disease associated with increased apo (a) or Lp (a), at an individual in need thereof.
EFFECT: reduced expression of apolipoprotein mRNA and protein in an animal, and can be used in medicine.
23 cl, 65 tbl, 13 ex
Title | Year | Author | Number |
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METHODS AND COMPOSITIONS FOR MODULATING EXPRESSION OF APOLIPOPROTEIN (A) | 2013 |
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RU2598709C2 |
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RU2661781C2 |
COMPOSITIONS AND METHODS FOR MODULATING EXPRESSION OF APOLIPOPROTEIN (A) | 2014 |
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RU2699985C2 |
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Authors
Dates
2017-06-30—Published
2013-05-23—Filed