METHOD FOR HIGHLY SENSITIVE IMMUNOCHROMATOGRAPHIC ANALYSIS WITH DOUBLE COMPETITION Russian patent published in 2021 - IPC G01N33/53 

Abstract RU 2748901 C1

FIELD: immunology; biochemistry.

SUBSTANCE: invention relates to immunology and analytical biochemistry and is a method for immunochromatographic analysis. The method for immunochromatographic competitive analysis involves the immobilization of specific antibodies against the compound to be determined on the surface of marker particles and in the test zone of the working membrane, while the formation of a colored complex in the test zone occurs when a conjugate of a carrier protein with several analyte molecules is added due to polyvalent interaction, and in the case of the presence in the sample of the compound to be determined, its molecules block the active centers of antibodies both on the marker particles and in the test zone.

EFFECT: increasing the sensitivity of the method.

1 cl, 3 dwg

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RU 2 748 901 C1

Authors

Sotnikov Dmitrii Vasilevich

Zherdev Anatolii Vitalievich

Dzantiev Boris Borisovich

Dates

2021-06-01Published

2020-09-30Filed