PHARMACEUTICAL COMPOSITION INCLUDING IMIDAZOLINE DERIVATIVE Russian patent published in 2021 - IPC A61K31/4166 A61K47/38 A61P35/00 

Abstract RU 2749135 C2

FIELD: pharmaceuticals.

SUBSTANCE: present invention relates to a pharmaceutical composition for the treatment and prevention of prostate cancer containing (S)-4-(3-(4-(2,3-dihydroxypropoxy) phenyl) - 4,4-dimethyl-5-carbonyl-2-thioimidazole n-1-yl) - 2-(trifluoromethyl)benzonitrile as the active ingredient and hydroxypropyl cellulose, which is present in an amount of 0.5 to 10 wt %, relative to the total weight of the pharmaceutical composition. The present invention also relates to a method for preparing the pharmaceutical composition and to the use of the pharmaceutical composition.

EFFECT: obtaining a composition that has good stability, dissolution rate and biological availability.

11 cl, 7 tbl, 8 ex

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RU 2 749 135 C2

Authors

Lu, Yun

Chzhan, Sinkhua

Chzhan, Dajmej

Dates

2021-06-04Published

2017-02-17Filed