FIELD: medicine.
SUBSTANCE: group of inventions relates to the field of medicine, namely, a prolonged-release tablet for the prevention and/or treatment of transthyretin-associated amyloidosis, containing micronized tolcapone, a cellulose polymer selected from the group consisting of cellulose esters and cellulose esters, and microcrystalline cellulose, and also relates to a method for the prevention and/or treatment of transtyretin-associated amyloidosis, as well as to the use of micronized tolcapone, as well as to a pharmaceutical composition in the form of a tablet and the method for manufacturing the tablet.
EFFECT: group of inventions provides for the production of a prolonged-release tablet containing tolcapone.
15 cl, 1 dwg, 5 ex, 8 tbl
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Authors
Dates
2021-06-30—Published
2017-07-28—Filed