COMPOSITIONS CONTAINING NICOTINE AMIDRIBOSIDE AND UROLITIN Russian patent published in 2021 - IPC A61K31/366 A61K31/706 A61P21/00 A61P25/28 

FIELD: medicine; pharmaceuticals.

SUBSTANCE: group of inventions relates to the field of medicine and pharmaceuticals. Objects 1 and 6 are a composition and kit for improving mitochondrial function, containing nicotinamidriboside and urolitin. Objects 2 and 5 are methods of treating a condition associated with muscle pathology, neurodegenerative disease and/or mitochondrial disease, or improving muscle function in a subject, including the administration of a composition or effective amounts of urolitin and nicotinamidriboside. Objects 3 and 4 are methods of maintaining, preventing a decrease or increase in muscle or physical functional indicators, increasing the endurance limit, increasing muscle mass and/or muscle growth, including the introduction of an effective amount of the composition to the subject.

EFFECT: synergistic effect of the combination of urolitin and nicotinamide riboside on mitochondrial function, mitochondrial biogenesis and autophagy.

28 cl, 4 dwg, 12 tbl, 8 ex