FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely, to methods for stimulating mitophagy. A method for stimulating autophagy in cells, involving treatment of cells with a terpenoid-based inducer, wherein the "Abisil", "Abisil-1" or "Abisil-2" agent is used as such a terpenoid-based inducer in an effective concentration. A method for stimulating autophagy in a subject, with a stage of introducing an effective dose of an inducer into the body, wherein the "Abisil", "Abisil-1" or "Abisil-2" agent is used as such an inducer and stimulation of autophagy ensures treatment of a condition associated with mitochondrial dysfunction.
EFFECT: above group of inventions provides a possibility of increasing the stability and effectiveness of impact on the cells and reducing the toxicity of plant-based agents, stimulating the process of eliminating dysfunctional cellular components by autophagy, leading to alleviation and treatment of conditions associated with mitochondrial dysfunction.
1 cl, 4 dwg, 2 tbl, 4 ex
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Authors
Dates
2022-01-31—Published
2020-09-30—Filed