FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, specifically to method for cultivation of T cells population containing chimeric antigen receptor (hereinafter – CAR); it can be used in medicine. The claimed method includes bringing a T cells population into a contact with a combination of cytokines including IL-15 and at least one cytokine selected from IL-2, IL-7, IL-12, IL-18 and IL-21.
EFFECT: method provides for a T cells population containing CAR, which is effectively used in cancer immunotherapy.
50 cl, 61 dwg, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD AND COMPOSITIONS FOR CELLULAR IMMUNOTHERAPY | 2015 |
|
RU2752275C2 |
| TRANSGENIC GENETIC LABELS AND METHODS OF USE | 2015 |
|
RU2822461C1 |
| TRANSGENIC GENETIC LABELS AND METHODS OF USING | 2015 |
|
RU2729112C2 |
| DRUG-REGULATED TRANSGENIC EXPRESSION | 2015 |
|
RU2751920C2 |
| METHOD AND COMPOSITIONS FOR CELL IMMUNOTHERAPY | 2013 |
|
RU2700765C2 |
| METHOD AND COMPOSITIONS FOR CELLULAR IMMUNOTHERAPY | 2012 |
|
RU2688185C2 |
| CHIMERIC RECEPTORS CONTAINING TRAF-6-INDUCING DOMAINS AND COMPOSITIONS AND METHODS RELATED TO THEM | 2016 |
|
RU2773159C2 |
| PRODUCTION OF CONSTRUCTED CELLS FOR ADOPTIVE CELL THERAPY | 2017 |
|
RU2780156C2 |
| METHODS FOR PRODUCING ALLOGENIC T-CELLS WITH CAR | 2020 |
|
RU2828787C2 |
| METHODS OF EXPANSION OF ANTIGEN-SPECIFIC CAR-T-CELLS, COMPOSITIONS AND THEIR USE | 2019 |
|
RU2800920C2 |
