ANTIBODY POLYPEPTIDES AND THEIR APPLICATION Russian patent published in 2021 - IPC C07K16/30 C12N15/13 A61K49/16 A61K39/395 

Abstract RU 2753677 C2

FIELD: biochemistry.

SUBSTANCE: invention relates to the field of biochemistry, in particular to an antibody or its antigen-binding fragment with the specificity of binding to a prostate-specific antigen (PSA). Isolated nucleic acid encoding the specified antibody, an expression vector containing the specified nucleic acid, a host cell containing the specified vector, a pharmaceutical composition, a conjugate, a set containing the specified antibody are also disclosed. The method for producing the specified antibody, the use of the specified antibody for the production of a drug for the treatment or diagnostics of prostate cancer, a method for the treatment or diagnostics using the specified antibody are disclosed.

EFFECT: invention makes it possible to effectively treat disorders associated with the specificity of binding to a prostate-specific antigen (PSA).

80 cl, 5 dwg, 3 tbl, 6 ex

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RU 2 753 677 C2

Authors

Tran, Amanda Thuy

Axelsson, Anders

Malmborg Hager, Cecilia Ann-Christin

Sjostrom, Kjell

Strand, Sven-Erik

Lamminmaki, Urpo Juhani

Dates

2021-08-19Published

2016-10-04Filed