ANTI-DR5 ANTIBODY AND USE THEREOF Russian patent published in 2020 - IPC C07K16/28 A61K39/395 A61P35/00 

Abstract RU 2735956 C1

FIELD: biochemistry.

SUBSTANCE: invention relates to death receptor 5 (DR5) antibody or antigen-binding fragment thereof, as well as a pharmaceutical composition containing it. Also disclosed is a polynucleotide molecule coding said antibody or its fragment, as well as a vector and a cell containing said molecule. Invention also relates to a method of producing an anti-DR5 antibody or antigen-binding fragment thereof, comprising a step of culturing said cell.

EFFECT: invention enables effective prevention or treatment of oncological diseases.

16 cl, 12 tbl, 15 ex, 11 dwg

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RU 2 735 956 C1

Authors

Doh Hyounmie

Lee Dongsop

Lee Hanyoung

Kim Yoojin

Han Kyungmi

Jung Eunee

Kim Donghyeon

Song Dongsup

Shin Kum-Joo

Woo Soyon

Dates

2020-11-11Published

2018-02-08Filed