FIELD: biotechnology.
SUBSTANCE: present invention relates to polyspecific antibodies and can be used in medicine. Invention discloses novel proteins which specifically bind to the NKG2D receptor, CD16 and the tumour-specific trophoblast cell surface antigen (TROP2).
EFFECT: invention can be used in medical practice as a therapeutic agent in the treatment of a number of malignant neoplasms, for example, gastrointestinal cancer, colorectal cancer, pancreatic cancer, non-small cell lung cancer and breast cancer.
25 cl, 37 dwg, 14 tbl, 10 ex
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PROTEIN BINDING WITH NKG2D, CD16 AND WITH TUMOR-SPECIFIC ANTIGEN | 2018 |
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Authors
Dates
2024-06-06—Published
2018-02-27—Filed