FIELD: medicine.
SUBSTANCE: invention relates to the field of medicine, in particular, to the field of development of therapeutic and cosmetic compositions and application thereof for delivery of inorganic particles, specifically cerium dioxide nanoparticles, through the skin. A composition for transdermal delivery of nanoparticles is proposed, containing dimethyl sulphoxide as a penetrator and nanocrystalline cerium dioxide as nanoparticles, bound to a stabiliser constituting a polysaccharide, with the following ratio of components, % wt.: cerium dioxide nanoparticles - 1.7; stabiliser - 8.3; dimethyl sulphoxide - 90. Low-molecular polyglucans can be used as a stabiliser.
EFFECT: ensures maximum penetration of cerium dioxide nanoparticles through the skin barrier to a depth of up to 20 mcm.
2 cl, 4 dwg, 4 ex
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