ISOLIC ACID PRODUCING YARROWIA LIPOLYTICA YEAST STRAIN Russian patent published in 2021 - IPC C12P7/48 C12N15/63 C12N1/19 

Abstract RU 2757603 C1

FIELD: microbiology.

SUBSTANCE: invention relates to microbiology and is a Yarrowia lipolytica 583 RNCIM Y-4657 yeast strain with an inactivated YlYHM2 gene and enhanced expression of the YlAMPD and YlSFC1 genes, producing isolic acid under conditions of an excess of a carbon source and a limit of a nitrogen source.

EFFECT: invention makes it possible to obtain isocitric acid with a high degree of efficiency.

1 cl, 2 dwg, 1 tbl, 2 ex

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RU 2 757 603 C1

Authors

Yuzbasheva Evgeniya Yurevna

Yuzbashev Tigran Vladimirovich

Laptev Ivan Aleksandrovich

Kosikhina Yuliya Mikhajlovna

Vinogradova Elizaveta Borisovna

Taratynova Mariya Olegovna

Shutov Artem Vladimirovich

Dementev Dmitrij Alekseevich

Sineokij Sergej Pavlovich

Dates

2021-10-19Published

2021-02-26Filed