FIELD: medicine.
SUBSTANCE: invention refers to a method of producing succinic acid with using a Yarrowia lipolytica yeast strain, Russian National Collection of Industrial Microorganisms No. Y-3314. Said yeast is modified in such a manner that they have lowered succinate dehydrogenase activity. The method involves a stage of yeast strain incubation in a nutrient medium containing glycerine, and recovery of succinic acid from a culture fluid.
EFFECT: use of the Yarrowia lipolytica strain, Russian National Collection of Industrial Microorganisms No Y-3314 has ensured substantially increased yield of succinic acid in this method.
2 cl, 2 dwg, 5 tbl, 5 ex
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Authors
Dates
2011-06-27—Published
2009-01-30—Filed