MODIFIED NUCLEOTIDE SEQUENCE ENCODING A POLYPEPTIDE WITH THE ACTIVITY OF PHYTOENE SYNTHASE AND GERANYLGERANYL PYROPHOSPHATE SYNTHASE (VARIANTS), ITS USE IN THE CONSTRUCTION OF CAROTENOID-PRODUCING YARROWIA LIPOLYTICA YEAST TRANSFORMANTS Russian patent published in 2023 - IPC C07K19/00 C12N15/81 C12P23/00 

Abstract RU 2794980 C1

FIELD: biotechnology.

SUBSTANCE: invention can be used to obtain carotenoids. Proposed are variants of the polynucleotide possessing the activity of phytoene synthase and geranylgeranyl pyrophosphate synthase. These polynucleotides are used to obtain Yarrowia lipolytica yeast transformants producing β-carotene, canthaxanthin or astaxanthin.

EFFECT: invention provides an increase in the production of carotenoids.

10 cl, 14 dwg, 10 tbl, 9 ex

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RU 2 794 980 C1

Authors

Yuzbasheva Evgeniya Yurevna

Taratynova Mariya Olegovna

Kosikhina Yuliya Mikhajlovna

Yuzbashev Tigran Vladimirovich

Dementev Dmitrij Alekseevich

Andreeva Natalya Igorevna

Fedorov Aleksandr Sergeevich

Sineokij Sergej Pavlovich

Dates

2023-04-26Published

2021-12-15Filed