FIELD: organic chemistry.
SUBSTANCE: invention relates to the field of organic chemistry, specifically to a method for obtaining esters of non-natural amino acids containing a heme-dichlorocyclopropane fragment. The method consists in the interaction of the corresponding secondary amine with the esters of monochloroacetic acid in the presence of potassium carbonate using microwave radiation for 30 minutes. Preferably, the reaction of the secondary amine with the esters of monochloroacetic acid is carried out at the following ratio of components, wt. %: secondary amine - 26; ether - 33; K2CO3 - 41.
EFFECT: proposed method makes it possible to increase the yield of the target product and reduce the reaction time.
1 cl, 1 ex
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