DRUG FOR INJECTION BASED ON SAPONIN B4 PULSATILLA Russian patent published in 2021 - IPC A61K9/08 A61K31/704 A61K36/71 

FIELD: pharmaceutics.

SUBSTANCE: group of inventions relates to the pharmaceutical industry, namely to a drug for injection based on saponin B4 Pulsatilla and a method for its preparation and lyophilized powder for injection based on saponin B4 Pulsatilla and a method for its preparation. The drug for injection based on saponin B4 Pulsatilla is lyophilized powder for injection, and pharmaceutically acceptable auxiliary substance is auxiliary substance for obtaining a lyophilized form, which is one or more auxiliary substances selected from a group consisting of lactose, sucrose and mannitol, in any ratio, while the mass ratio of saponin B4 Pulsatilla and an auxiliary substance for obtaining a lyophilized form in lyophilized powder for injection is from 3:10 to 3:16; lyophilized powder for injection is obtained in a certain way under certain conditions. A method for the preparation of lyophilized powder for injection based on saponin B4 Pulsatilla is proposed. Lyophilized powder for injection based on saponin B4 Pulsatilla is considered.

EFFECT: above-described group of inventions makes it possible to obtain lyophilized powder for injection based on saponin B4 Pulsatilla, which is stable, contains less water and impurities and is controlled by optimizing parameters of the preparation method.

10 cl, 10 tbl, 4 ex