FIELD: biotechnology.
SUBSTANCE: proposed is a method for detecting copy number variations and changes in the BRCA1 and BRCA2 genes.
EFFECT: invention ensures more accurate detection of not only germinal copy number variations in the BRCA1 and BRCA2 genes, but also somatic copy number changes, as well as reduction of the cost of analysis.
4 cl, 1 tbl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR BRCA1 AND BRCA2 GENES EXONS NUCLEOTIDE SEQUENCE DETERMINATION | 2015 |
|
RU2612894C1 |
| METHOD OF DETECTING COPY NUMBER VARIATIONS (CNV) BASED ON SEQUENCING DATA OF COMPLETE HUMAN EXOME AND LOW-COVERAGE GENOME | 2023 |
|
RU2822040C1 |
| METHOD OF CREATING TARGET PANEL FOR STUDYING GENOMIC REGIONS FOR DETECTING THERAPEUTIC BIOMARKERS OF IMMUNE CHECKPOINT (IC) INHIBITORS | 2023 |
|
RU2818360C1 |
| WHOLE GENOME SEQUENCING DATA PROCESSING SYSTEM | 2023 |
|
RU2806429C1 |
| DIAGNOSTIC METHOD OF PREDISPOSITION TO BREAST CANCER IN RUSSIAN POPULATION BASED ON PCR-RFLP | 2018 |
|
RU2723585C2 |
| METHOD FOR PREDICTION OF RISK OF MALIGNANT DISEASES OF MAMMARY GLAND AND/OR OVARIES IN PATIENTS AFTER KIDNEY TRANSPLANTATION | 2023 |
|
RU2821583C1 |
| WHOLE GENOME SEQUENCING DATA PROCESSING SYSTEM | 2023 |
|
RU2804535C1 |
| INDIVIDUALISED VACCINES FOR CANCER | 2012 |
|
RU2670745C9 |
| METHOD OF ANALYZING TERMINAL MUTATIONS IN BRCA1, BRCA2, ATM AND PALB2 GENES USING MULTIPLEX PCR AND SUBSEQUENT HYBRIDISATION WITH AN OLIGONUCLEOTIDE BIOLOGICAL MICROCHIP (BIOCHIP) | 2020 |
|
RU2729360C1 |
| METHOD FOR MOLECULAR-GENETIC DIAGNOSIS OF HEREDITARY BREAST CANCER | 2019 |
|
RU2702755C1 |
