COMBINATION THERAPIES FOR THE TREATMENT OF CANCER Russian patent published in 2021 - IPC A61K31/452 A61K31/7068 A61P35/00 

FIELD: medicine.

SUBSTANCE: group of inventions relates to medicine and concerns a method for the treatment of myelodysplastic syndrome (hereinafter – MDS) including injection of therapeutically effective amount of a combination therapy containing decitabine or its pharmaceutically acceptable salt and alvocidib or its pharmaceutically acceptable salt to a person who needs it, where decitabine or its pharmaceutically acceptable salt is injected to a person before alvocidib or its pharmaceutically acceptable salt. The group of inventions also concerns a method for the treatment of MDS including injection of therapeutically effective amount of a combination therapy containing azacytidine or its pharmaceutically acceptable salt and alvocidib or its pharmaceutically acceptable salt to a person; a kit for the treatment of MDS containing a combination including alvocidib or its pharmaceutically acceptable salt and decitabine or azacytidine or their pharmaceutically acceptable salts; and instructions.

EFFECT: group of inventions provides for synergetic effect when treating MDS.

11 cl, 5 dwg, 4 ex