POLYSACCHARIDE COMPOSITIONS FOR RESTORING TISSUES Russian patent published in 2021 - IPC A61K31/722 A61K31/728 A61P17/02 A61P19/00 A61P19/02 A61P19/04 

Abstract RU 2760358 C2

FIELD: pharmacology; medicine.

SUBSTANCE: invention relates to the field of pharmacology and medicine, namely to the modulation of cell proliferation processes. The use of a polysaccharide composition, containing hyaluronic acid and an oligosaccharide derivative of chitosan obtained in a reaction of reductive amination of D-glucosamine with lactose, which has a degree of substitution of an amine functional group of D-glucosamine with lactose of at least 40%, is described to modulate cell proliferation, which leads to tissue restoration and/or prevention of fibrosis and/or tissue adhesions, while the specified hyaluronic acid is present in the amount from 1.0 mg/ml or 1.25 mg/ml, and the specified oligosaccharide derivative of chitosan and lactose is present in the amount from 0.1 to 1.5 mg/ml.

EFFECT: providing modulation of cell proliferation processes, which is effectively used in tissue restoration to prevent fibrotic processes and/or the formation of tissue adhesions in traumatic, postoperative and chronic fibrotic processes associated with autoimmune diseases.

13 cl, 4 dwg, 3 tbl, 4 ex

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RU 2 760 358 C2

Authors

Kallegaro, Lanfranko

Brun, Paola

Byanchini, Dzhulio

Dates

2021-11-24Published

2017-06-06Filed