COMPOSITION CONTAINING COMPOUND OF BENZOIC ACID AMIDE AND SOLUBILIZING AGENT CYCLODEXTRIN Russian patent published in 2021 - IPC A61K31/166 A61K8/42 A61K31/724 A61K8/73 A61K47/40 A61Q19/02 

Abstract RU 2761622 C2

FIELD: medicine; cosmetology.

SUBSTANCE: present invention relates to the field of medicine, namely to cosmetology; it is intended for skin whitening, while a cosmetic composition contains dissolved substance that is 5-adamantane-1-yl-N-(2,4-dihydroxybenzoyl)-2,4-dimethoxy-amide of benzoic acid or its pharmaceutically acceptable salt, and the first solubilizer that is cyclodextrin, where cyclodextrin includes hydroxypropyl-β-cyclodextrin and γ-cyclodextrin in a mass ratio of 1: from 0.1 to 10, and a mass ratio of dissolved substance and the first solubilizer is 1: from 1 to 20, and where the content of dissolved substance is from 0.01 to 20 wt.% of the total weight of the composition.

EFFECT: improved solubility of 5-adamantane-1-yl-N-(2,4-dihydroxybenzoyl)-2,4-dimethoxy-amide of benzoic acid or its pharmaceutically acceptable salt in the composition of the cosmetic composition for skin whitening.

6 cl, 3 dwg, 13 tbl, 16 ex

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RU 2 761 622 C2

Authors

I,Chan-Gyn

Kim, Suil

Park, Sun Il

Sin, Khon-Yu

Dates

2021-12-13Published

2018-03-26Filed