MEDICAMENT Russian patent published in 2019 - IPC A61K38/17 A61K31/7088 A61P35/00 A61K39/395 

Abstract RU 2709015 C2

FIELD: medicine.

SUBSTANCE: group of inventions relates to medicine and concerns a medicinal agent for treating cancer, comprising a Toll-like receptor agonist and a LAG-3 protein, a variant or derivative thereof, where the Toll-like receptor agonist is Toll-like receptor 3 agonist, and the LAG-3 protein, a variant or derivative thereof is a fusion protein of LAG-3 and IgG protein. Group of inventions also relates to using a combination comprising a Toll-like receptor agonist and a LAG-3 protein, a variant or derivative thereof, for inducing a specific immune response against a cancer cell.

EFFECT: group of inventions provides reducing the tumour size and increasing the survival rate.

11 cl, 1 ex, 26 dwg

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RU 2 709 015 C2

Authors

Tamada, Koji

Doi, Shun

Miyakawa, Tomoya

Dates

2019-12-13Published

2016-04-07Filed