COMPOSITIONS AND METHODS FOR THE TREATMENT OF AUTOIMMUNE DISEASES AND CANCER Russian patent published in 2021 - IPC A61K38/00 A61K39/395 A61P35/00 

Abstract RU 2761980 C2

FIELD: medicine.

SUBSTANCE: group of inventions relates to a method for the treatment of cancer, a method for reducing the size of tumor, a method for increasing survivability of a subject having cancer, a method for increasing an immune response against tumor, a method for the treatment of an autoimmune disease, and a method for weakening an inflammatory response in a subject who needs it, including injection to a subject of effective amount of a siglek-15 modulator, where the modulator reduces expression and/or activity of siglek-15 in a subject, where the modulator contains an antagonistic antibody to siglek-15 or its antigen-binding fragment and/or a recombinant fused protein of siglek-15.

EFFECT: group of inventions provides for the effective treatment of cancer, reduction in the size of tumor, increase in survivability, increase in an immune response against tumor, autoimmune disease, weakening of an inflammatory response.

44 cl, 27 dwg, 18 ex

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RU 2 761 980 C2

Authors

Chen, Lieping

Wang, Jun

Sun, Jingwei

Dates

2021-12-14Published

2016-11-09Filed