METHOD FOR PRODUCING 3,7-BIS-(DIMETHYLAMINO)-PHENOTHIAZINE-5ii CHLORIDE OR BROMIDE Russian patent published in 2021 - IPC C07D279/18 C07D279/20 A61K31/5415 

Abstract RU 2762826 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a new method for producing 3,7-bis-(dimethylamino)-phenothiazine-5ii chloride or bromide, as well as to the use of 3,7-dichlorphenothiazine-5-ii chloride as an intermediate compound.

EFFECT: improved method for producing 3,7-bis-(dimethylamino)-phenothiazine-5ii chloride or bromide is proposed, where isolation and/or purification of any intermediate reaction compound is not used after the reaction of phenothiazine with suitable halogen; the method, according to the invention, allows for exclusion of time need for isolation and purification of intermediate compounds, reduction of industrial waste.

11 cl, 1 tbl, 6 ex

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RU 2 762 826 C2

Authors

Benadikova Daniela

Cech Juraj

Juhas Erik

Oremus Vladimir

Smahovsky Vendel

Dates

2021-12-23Published

2018-03-15Filed