METHOD FOR SYNTHESIS OF MANDIPROPAMID AND DERIVATIVES THEREOF Russian patent published in 0 - IPC C07C231/02 C07C231/12 C07C217/60 C07C235/34 C07C251/16 C07C255/37 C07C33/46 C07C33/48 C07C59/70 C07C69/734 C07C315/04 C07C317/46 C07C319/20 C07C323/62 C07C43/176 C07C43/313 C07C231/00 C07C33/00 C07C43/00 

Abstract RU 2470914 C9

FIELD: chemistry.

SUBSTANCE: disclosed is a method of producing a compound of formula (I), where N equals 0, and values of substitutes R, R1 are given in claim 1, which involves: (i) esterification of a compound of formula (V) with an alcohol of formula , where m and m' are independently equal to 0 or 1; under the condition that both are not equal to 0 at the same time and values of A are given in claim 1, to obtain a compound of formula (III); (ii) reaction of the compound of formula (III) and a compound of formula (IV) to obtain a compound of formula (II); and (iii) reaction of the compound of formula (II) with L-CH2-C≡CH, wherein L is a leaving group, to form a compound of formula (I); intermediate compounds of formula (II), formula (III) and formula (XII) are also disclosed.

EFFECT: improved method.

15 cl, 19 ex, 1 dwg

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RU 2 470 914 C9

Authors

Bouden Martin Charl'Z

Klark Tomas Ehjtcheson

Zhiordano Fanni Del'Fin Brizhitt

Zho Beat

Shnajder Khans-Diter

Zajfert Gottfrid

Viss Jurg

Tseller Martin

Faber Dominik

Dates

Published

2006-08-08Filed