FIELD: chemistry.
SUBSTANCE: invention refers to medicine, pharmacology and chemical-pharmaceutical industry, namely to a method of producing a compound of formula (I). Method is carried out by reacting a compound of formula (II)' with an organic fluorine-containing acid in a mixture of solvents, which is a mixture of an aprotic organic solvent with water in a volume ratio of 1.0:10.0-10.0:1.0, respectively, and a mixture of bases consisting of an inorganic base selected from a group comprising hydroxides of alkali, alkali-earth metals or ammonium, or hydrates thereof, and alkylamine, in molar ratios of inorganic base to alkylamine from 1.0:0.1 to 1.0:10.0.
EFFECT: disclosed method enables to obtain a compound of formula (I) with high output and purity.
9 cl, 1 dwg, 2 tbl, 2 ex
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Authors
Dates
2025-02-25—Published
2024-05-02—Filed