FIELD: medicine.
SUBSTANCE: present invention relates to a class of cyclopropylamine compounds, namely to a compound of the formula (I), its pharmaceutically acceptable salt or its tautomer,
where values of f, r, e, p, m, n, R1, R2, R3, R4 and R6 are such as defined in the formula of the invention. Pharmaceutical compositions and the use of a compound of the formula (I) in the manufacture of LSD1 inhibitors and a drug for the treatment of lung cancer are also proposed.
EFFECT: obtaining new organic compounds that are inhibitors of lysin-specific demethylase 1 (LSD1).
29 cl, 8 tbl, 246 ex
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Authors
Dates
2022-01-11—Published
2018-01-24—Filed