SODIUM SALT OF 4-{ 2-[2-(4- HYDROXY-3-METHOXYPHENYL)-VINYL]-6-ETHYL-4-OXO-5-PHENYL-4H-PYRIMIDINE-1-YL} -BENZENESULFAMIDE, WHICH HAS AN ANTITUMOR EFFECT Russian patent published in 2022 - IPC A61K31/00 A61K31/505 C07D239/36 A61P35/00 

Abstract RU 2763899 C1

FIELD: medicine.

SUBSTANCE: present invention relates to the field of medicine, namely oncology, and reveals the use of sodium salt 4-{2-[2-(4-hydroxy-3-methoxyphenyl)-vinyl]-6-ethyl-4-oxo-5-phenyl-4H-pyrimidine-1-yl}-benzosulfamide, of formula I, as a remedy with antitumor effect in melanoma.

EFFECT: pronounced cytostatic activity of the sodium salt 4-{2-[2-(4-hydroxy-3-methoxyphenyl)-vinyl]-6-ethyl-4-oxo-5-phenyl-4H-pyrimidine-1-yl}-benzosulfamide, of formula I, which has an antitumor effect in melanoma.

1 cl, 3 tbl

Формула I – Formula I

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RU 2 763 899 C1

Authors

Kit Oleg Ivanovich

Kodonidi Ivan Panaiotovich

Glushko Aleksandr Alekseevich

Frantsiiants Elena Mikhailovna

Oganesian Eduard Tonikovich

Chernikov Maksim Valentinovich

Kaplieva Irina Viktorovna

Anenko Denis Stanislavovich

Chiriapkin Aleksei Sergeevich

Dates

2022-01-11Published

2021-03-26Filed