ORAL CARE COMPOSITION FOR SUPPRESSING DENTIN HYPERESTHESIA Russian patent published in 2022 - IPC A61K8/34 A61K8/49 A61K8/64 A61K8/86 A61Q11/00 

FIELD: hygiene.

SUBSTANCE: group of inventions relates to an oral care composition and a method for use thereof. Proposed is an oral care composition for suppressing dentin hyperesthesia, containing a peptide consisting of an amino acid sequence selected from SEQ ID NO: 81 to 96. Said composition comprises: 0.00005 to 0.00015 mass parts of the peptide, 85 to 87 mass parts of purified water, 1.7 to 2.9 mass parts of a surface-active agent selected from a poloxamer and/or polysorbate 20, 0.545 to 0.555 mass parts of cetylpyridinium chloride, 9 to 11 mass parts of a humidifying agent selected from a solution of D-sorbitol and/or concentrated glycerin, and 0.0045 to 0.0055 mass parts of citric acid hydrate as calculated per 100 mass parts of the composition. Also proposed is a method for suppressing dentin hyperesthesia in a subject in need thereof by exposing the dentin surface in said subject to the above composition.

EFFECT: use of the composition ensures prevention or suppression of dentin hyperesthesia by eliminating defects in the dentin tubules and clogging of open dentin tubules due to the physiological remineralisation of dentin.

4 cl, 7 dwg, 26 tbl, 3 ex