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(19)

RU

(11)

2 773 055

(13)

C2

(51)

IPC

C07K14/47(2006-01-01)

A61K38/16(2006-01-01)

A61P43/00(2006-01-01)

(21) (22)

Application

2019137603, 2018-04-24

(24)

Start date

2018-04-24

(22)

Actual filing date

2018-04-24

(45)

Published

2022-05-30

(72)

Inventor

Nihashi, YoichiroKawachi, TomoyukiYamatsu, YukikoFumoto, MasatakaYamazaki, Takehiko

(73)

Holder

Shionogi Co., Ltd.Stemrim Inc.

PEPTIDE FOR INDUCING TISSUE REGENERATION AND ITS USE Russian patent published in 2022 - IPC C07K14/47 A61K38/16 A61P43/00 

Abstract RU 2773055 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology, specifically to therapeutic peptides originating from human HMGB1; it can be used in medicine for tissue regeneration. Modified peptides are obtained based on a human HMGB1 fragment, having activity relatively to migration of stromal and mesenchymal cells of bone marrow origin, in particular PDGFRα-positive cells, and increased stability in blood plasma compared to an unmodified human HMGB1 fragment 2-44.

EFFECT: obtaining peptides for tissue regeneration.

8 cl, 1 tbl, 6 ex, 3 dwg

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RU 2 773 055 C2

Authors

Nihashi, Yoichiro

Kawachi, Tomoyuki

Yamatsu, Yukiko

Fumoto, Masataka

Yamazaki, Takehiko

Dates

2022-05-30—Published

2018-04-24—Filed

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