ANTIBODIES SPECIFIC FOR CD70 AND THEIR USE Russian patent published in 2023 - IPC C07K16/28 A61K39/395 A61P35/00 

Abstract RU 2801093 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to an isolated antibody that specifically binds to the differentiation cluster 70 (CD70), a method of its production, as well as to a composition containing it. Also an isolated nucleic acid encoding the above antibody is disclosed, as well as a vector and a cell containing it is disclosed. The invention also relates to a bispecific antibody that specifically binds to CD70, a method of its preparation, and a composition containing it. Also a nucleic acid molecule encoding the above bispecific antibody, as well as a cell and a vector containing it are disclosed.

EFFECT: invention is effective as a medicinal product for the treatment of cancer associated with CD70.

31 cl, 5 tbl, 3 ex

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RU 2 801 093 C2

Authors

Panowski, Siler

Sai, Tao

Sasu, Barbra Johnson

Srivatsa Srinivasan, Surabhi

Van Blarcom, Thomas John

Dates

2023-08-01Published

2019-01-31Filed