ANTIBODIES DIRECTED AGAINST Fc-RECEPTOR-LIKE PROTEIN 5 AND METHODS FOR THEIR APPLICATION Russian patent published in 2022 - IPC C07K16/28 A61K39/395 G01N33/68 A61P35/00 

Abstract RU 2774158 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology, in particular to an isolated anti-Fc receptor-like protein 5 (FcRL5) antibody or its antigen-binding fragment, as well as to a composition, an immunoconjugate, a bispecific molecule and a kit containing it. Also disclosed is a nucleic acid molecule encoding said antibody or fragment thereof, as well as a vector and a host cell containing it. The invention also relates to a method for detecting FcRL5 in a whole cell or tissue, comprising contacting the cell or tissue with the above anti-FcRL5 antibody or antigen-binding fragment thereof.

EFFECT: invention is effective for treating a tumor expressing FcRL5.

66 cl, 16dwg, 232 tbl ,5 ex

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RU 2 774 158 C2

Authors

Brentjens Renier J.

Smith Eric L.

Liu Cheng

Dates

2022-06-15Published

2016-12-02Filed