FIELD: genetic engineering; biotechnology.
SUBSTANCE: group of inventions relates to the field of genetic engineering and biotechnology, namely to a guide RNA molecule, a ribonucleoprotein complex of the CRISPR/Cas system containing a guide RNA molecule, and to a set containing a ribonucleoprotein complex of the CRISPR/Cas system and specific oligonucleotides for pre-amplification of a highly conserved section of the SARS-CoV-2 virus genome.
EFFECT: inventions make it possible to effectively detect the RNA of the SARS-CoV-2 virus after specific amplification of a fragment of the genome of this virus and provide detection of single copies of the SARS-CoV-2 virus RNA.
7 cl, 11 dwg, 5 tbl, 5 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR DETECTING SARS-CoV-2 VIRUS RNA IN ULTRA-LOW CONCENTRATIONS AND SPECIFIC OLIGONUCLEOTIDES FOR USE IN THE METHOD | 2021 |
|
RU2764021C1 |
| METHOD FOR OBTAINING A PREPARATION OF THE CRISPR/Cas 12 RIBONUCLEOPROTEIN COMPLEX AND PREPARATION FOR DETECTING SARS-CoV-2 VIRUS RNA IN ULTRA-LOW CONCENTRATIONS | 2021 |
|
RU2764015C1 |
| METHOD OF OBTAINING A PREPARATION OF THE RIBONUCLEOPROTEIN COMPLEX CRISPR-CAS12 AND A PREPARATION FOR DETECTING HUMAN IMMUNODEFICIENCY VIRUS (HIV-1) RNA IN ULTRA-LOW CONCENTRATIONS | 2022 |
|
RU2802781C1 |
| METHOD OF DETECTION OF RNA OF HEPATITIS C VIRUS GENOTYPES 1B AND 3A IN ULTRA-LOW CONCENTRATIONS AND SPECIFIC OLIGONUCLEOTIDES FOR USE IN THE METHOD | 2022 |
|
RU2802079C1 |
| METHOD FOR OBTAINING A PREPARATION OF THE RIBONUCLEOPROTEIN COMPLEX CRISPR / Cas14 AND A PREPARATION FOR DETECTING THE RNA OF THE SARS-CoV-2 VIRUS IN ULTRA-LOW CONCENTRATIONS | 2021 |
|
RU2764024C1 |
| CRISPR-CAS14 SYSTEM FOR DETECTING SARS-CoV-2 VIRUS RNA AT ULTRA-LOW CONCENTRATIONS | 2021 |
|
RU2764020C1 |
| METHOD FOR DETECTING SARS-CoV-2 VIRUS RNA AT ULTRA-LOW CONCENTRATIONS AND SPECIFIC OLIGONUCLEOTIDES FOR USE IN THE METHOD | 2021 |
|
RU2764022C1 |
| CRISPR-CAS12 SYSTEM FOR DETECTING HUMAN IMMUNODEFICIENCY VIRUS (HIV-1) RNA IN ULTRA-LOW CONCENTRATIONS IN ULTRA-LOW CONCENTRATIONS | 2022 |
|
RU2802783C1 |
| METHOD FOR DETECTING ANTIBIOTIC RESISTANCE GENE bla-TEM-1B IN ULTRA-LOW CONCENTRATIONS AND SPECIFIC OLIGONUCLEOTIDES FOR USE IN METHOD | 2023 |
|
RU2820306C1 |
| METHOD FOR PRODUCING AN AGENT OF THE RIBONUCLEOPROTEIN COMPLEX CRISPR-Cas12 AND AGENT FOR DETECTING THE DNA OF THE HEPATITIS B VIRUS IN ULTRA-LOW CONCENTRATIONS | 2021 |
|
RU2792891C1 |
