SYSTEM AND METHOD FOR ESTIMATING BLOOD VOLUME IN THE BRAIN, AND/OR BLOOD FLOW IN THE BRAIN, AND/OR DEPTH OF ANESTHESIA OF A PATIENT Russian patent published in 2022 - IPC A61B5/295 A61B5/374 

Abstract RU 2766409 C2

FIELD: medicine.

SUBSTANCE: group of inventions relates to a system and method for estimating blood volume in the brain and/or blood flow in the brain, and/or depth of anesthesia of a patient. Excitation signal is supplied using an excitation electrode placed on the patient's head. Measurement signal (VC) caused by the excitation signal is sensed using a sensing electrode placed on the patient's head. Measurement signal (VC) is processed using a signal processor (VC) to determine an output indicative of a cerebral blood volume and/or cerebral blood flow. Using a processor device, noise in the measurement signal (VC) is reduced by applying a nonlinear noise reduction algorithm. During processing, based on the version with reduced noise of the signal (VC) of the measurement, the blood volume correlate in the brain is determined according to the area (A) obtained on the basis of integration of the measurement signal (VC). Area (A) is obtained based on integration of the measurement signal (VC) by the left ventricular ejection period (LVET), which is estimated as a period from a point (B) defined by at least a derivative of a voltage curve (DVC) before a maximum point (C), to point (X) defined at least by derivative of voltage curve (DVC) immediately after said maximum point (C). During processing, a brain blood volume correlate and/or a brain blood flow correlate is supplied to a first nonlinear model to obtain output values, indicating the volume of blood in the brain and/or blood flow in the brain. During processing, said output values are fed into a second nonlinear model to obtain final output values of blood volume in brain and/or blood flow in brain and/or output value indicating depth of anesthesia.

EFFECT: higher accuracy of estimating blood volume in the brain and/or blood flow in the patient's brain.

22 cl, 8 dwg

Similar patents RU2766409C2

Title Year Author Number
METHOD AND DEVICE FOR STUDYING FUNCTIONAL STATE OF BRAIN AND METHOD FOR MEASURING SUBELECTRODE RESISTANCE 2003
  • Zakharov S.M.
  • Skomorokhov A.A.
  • Smirnov B.E.
RU2252692C2
METHOD AND DEVICE FOR STUDYING FUNCTIONAL STATE OF BRAIN 2003
  • Zakharov S.M.
  • Skomorokhov A.A.
  • Smirnov B.E.
RU2248745C1
METHOD FOR NORMALIZING FUNCTIONAL STATE OF HUMAN ORGANISM BY ACTING UPON BRAIN 2004
  • Zvonikov Vjacheslav Mikhajlovich
  • Grishchenko Andrej Viktorovich
  • Filatov Igor' Alekseevich
  • Gerasin Igor' Konstantinovich
RU2289445C2
DEVICE FOR EXAMINATION OF BRAIN BIOLOGICAL ACTIVITY 1993
  • Zakharov Sergej Mikhajlovich
  • Smirnov Boris Evgen'Evich
  • Skomorokhov Anatolij Aleksandrovich
  • Tsyganok Vasilij Fedorovich
RU2076625C1
METHOD FOR FORMING BRAIN-COMPUTER CONTROL SYSTEM 2019
  • Bobe Anatolij Sergeevich
  • Rashkov Grigorij Vadimovich
  • Fastovets Dmitrij Vladislavovich
RU2704497C1
METHOD OF BRAIN EXAMINATION AND DEVICE INTENDED FOR ITS REALIZATION 1994
  • Blatov Igor' Vladimirovich
RU2103912C1
DEVICE FOR NORMALIZING RHYTHMS OF HUMAN BRAIN 2004
  • Sarapul'Tsev Petr Alekseevich
  • Pestrjaev Vladimir Anatol'Evich
  • Godlevskij Vladimir Ustinovich
  • Abuzjarov Farid Nikolaevich
  • Dudin Dmitrij Nikolaevich
RU2268642C1
METHOD AND DEVICE FOR DETERMINING ISCHEMIC BRAIN CONDITION 2018
  • Sulimanov Rushan Abdulkhakovich
  • Bichurin Mirza Imamovich
  • Petrov Roman Valerevich
  • Rebinok Anatolij Vladimirovich
  • Lobekin Vyacheslav Nikolaevich
RU2693819C1
METHOD FOR NON-INVASIVE LOW-CURRENT ELECTRICAL STIMULATION OF BRAIN STRUCTURES 2023
  • Trofimov Aleksei Olegovich
  • Martynov Dmitrii Sergeevich
  • Trofimova Kseniia Alekseevna
RU2820133C1
METHOD OF BRAIN STIMULATION 2023
  • Gordleeva Susanna Iurevna
  • Kurkin Semen Andreevich
  • Grigorev Nikita Andreevich
  • Savosenkov Andrei Olegovich
  • Maksimenko Vladimir Aleksandrovich
  • Khramov Aleksandr Evgenevich
  • Kazantsev Viktor Borisovich
RU2822811C1

RU 2 766 409 C2

Authors

Jensen, Erik, Weber

Gonzalez Pijuan, Carmen

Dates

2022-03-15Published

2018-05-29Filed