FIELD: medicine.
SUBSTANCE: group of inventions relates to a system and method for estimating blood volume in the brain and/or blood flow in the brain, and/or depth of anesthesia of a patient. Excitation signal is supplied using an excitation electrode placed on the patient's head. Measurement signal (VC) caused by the excitation signal is sensed using a sensing electrode placed on the patient's head. Measurement signal (VC) is processed using a signal processor (VC) to determine an output indicative of a cerebral blood volume and/or cerebral blood flow. Using a processor device, noise in the measurement signal (VC) is reduced by applying a nonlinear noise reduction algorithm. During processing, based on the version with reduced noise of the signal (VC) of the measurement, the blood volume correlate in the brain is determined according to the area (A) obtained on the basis of integration of the measurement signal (VC). Area (A) is obtained based on integration of the measurement signal (VC) by the left ventricular ejection period (LVET), which is estimated as a period from a point (B) defined by at least a derivative of a voltage curve (DVC) before a maximum point (C), to point (X) defined at least by derivative of voltage curve (DVC) immediately after said maximum point (C). During processing, a brain blood volume correlate and/or a brain blood flow correlate is supplied to a first nonlinear model to obtain output values, indicating the volume of blood in the brain and/or blood flow in the brain. During processing, said output values are fed into a second nonlinear model to obtain final output values of blood volume in brain and/or blood flow in brain and/or output value indicating depth of anesthesia.
EFFECT: higher accuracy of estimating blood volume in the brain and/or blood flow in the patient's brain.
22 cl, 8 dwg
Title | Year | Author | Number |
---|---|---|---|
METHOD AND DEVICE FOR STUDYING FUNCTIONAL STATE OF BRAIN AND METHOD FOR MEASURING SUBELECTRODE RESISTANCE | 2003 |
|
RU2252692C2 |
METHOD AND DEVICE FOR STUDYING FUNCTIONAL STATE OF BRAIN | 2003 |
|
RU2248745C1 |
METHOD FOR NORMALIZING FUNCTIONAL STATE OF HUMAN ORGANISM BY ACTING UPON BRAIN | 2004 |
|
RU2289445C2 |
DEVICE FOR EXAMINATION OF BRAIN BIOLOGICAL ACTIVITY | 1993 |
|
RU2076625C1 |
METHOD FOR FORMING BRAIN-COMPUTER CONTROL SYSTEM | 2019 |
|
RU2704497C1 |
METHOD OF BRAIN EXAMINATION AND DEVICE INTENDED FOR ITS REALIZATION | 1994 |
|
RU2103912C1 |
DEVICE FOR NORMALIZING RHYTHMS OF HUMAN BRAIN | 2004 |
|
RU2268642C1 |
METHOD AND DEVICE FOR DETERMINING ISCHEMIC BRAIN CONDITION | 2018 |
|
RU2693819C1 |
METHOD FOR NON-INVASIVE LOW-CURRENT ELECTRICAL STIMULATION OF BRAIN STRUCTURES | 2023 |
|
RU2820133C1 |
METHOD OF BRAIN STIMULATION | 2023 |
|
RU2822811C1 |
Authors
Dates
2022-03-15—Published
2018-05-29—Filed