FIELD: biotechnology.
SUBSTANCE: present invention relates to lipophilic nanoparticles carrying matrix RNA with an open reading frame of bound nucleosides coding human interleukin-12 (IL12), its functional fragments and fusion proteins, including IL12.
EFFECT: invention can be used in medical practice to produce a drug applicable in therapy of various tumor diseases.
142 cl, 38 dwg, 17 ex, 11 tbl
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