FIELD: biotechnology.
SUBSTANCE: invention relates to an antibody or an antigen-binding fragment thereof, which specifically bind to human CD127, as well as a composition and a kit containing it. Also disclosed is a combination of isolated nucleic acid molecules coding said antibody or antigen-binding fragment thereof.
EFFECT: invention is effective for treating a condition relieved or prevented by antagonizing IL7-R signaling induced by IL7.
29 cl, 11 dwg, 6 tbl, 10 ex
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