FIELD: chemistry.
SUBSTANCE: invention relates to new chemical synthesis, new intermediate compounds and catalysts used for obtaining sacubitril – neprilysin (NEP) inhibitor. It additionally relates to new intermediate compounds and their application for the path of the specified new chemical synthesis. Thus, for example, the invention relates to a new compound of the formula (XV) or its salt, in which R5 is selected from hydrogen and -CO-OR* group, and Ra and R* are independently selected from hydrogen and C1-C6-alkyl.
EFFECT: obtaining new intermediate compounds.
18 cl, 13 ex
Title | Year | Author | Number |
---|---|---|---|
NEW PYRIDAZINONE HERBICIDES | 2016 |
|
RU2764746C2 |
NEW QUINOLINE DERIVATIVES | 2019 |
|
RU2792933C2 |
NEW CONDENSED PYRIMIDINE COMPOUND OR SALT THEREOF | 2017 |
|
RU2770727C2 |
NEW BICYCLIC PYRAZOLE DERIVATIVES | 2018 |
|
RU2781426C2 |
NEW FIVE-MEMBER HETEROCYCLES, THEIR PREPARING, THEIR APPLYING AND PHARMACEUTICAL PREPARATIONS COMPRISING THEREOF | 1998 |
|
RU2240326C2 |
BENZOTRIAZOL AND TOLYLTRIAZOLE DERIVATIVES TO REDUCE CORROSION | 2017 |
|
RU2749854C2 |
PYRAZOLOPYRIDINE DERIVATIVES AS KINASE INHIBITORS | 2015 |
|
RU2733400C2 |
NEW AZAQUINOLINE DERIVATIVES | 2018 |
|
RU2773290C2 |
NEW BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS MEDICINAL AGENTS | 2004 |
|
RU2369601C2 |
TRICYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITION CONTAINING THEM AND USING THEM FOR TREATING IMMUNOLOGICAL AND ONCOLOGICAL COMPOUNDS | 2009 |
|
RU2545023C9 |
Authors
Dates
2022-03-31—Published
2016-12-08—Filed