FIELD: biotechnology; medicine.
SUBSTANCE: invention relates to biotechnology and medicine. The method for assessing the primary response to the combined chemotherapy before treatment is proposed, for which polymorphic alleles of АРОЕ - ɛ2, АРОЕ - ɛ3, АРОЕ - ɛ4 are detected.
EFFECT: method makes it possible to quickly obtain a noninvasively significant criterion for assessing the prognosis of the risk of developing a negative response to combined CT for patients with sporadic advanced ovarian cancer, which is a useful addition to the diagnostic complex for screening patients in the preoperative period and individualizes the approach to the treatment of patients with ovarian cancer.
1 cl, 4 dwg, 10 tbl, 3 ex
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Authors
Dates
2022-04-01—Published
2021-07-21—Filed