METHOD FOR ASSESSING PRIMARY RESPONSE TO COMBINED CHEMOTHERAPY OF SPORADIC OVARIAN CANCER OF STAGES III AND IV Russian patent published in 2022 - IPC C12Q1/68 

Abstract RU 2769543 C2

FIELD: biotechnology; medicine.

SUBSTANCE: invention relates to biotechnology and medicine. The method for assessing the primary response to the combined chemotherapy before treatment is proposed, for which polymorphic alleles of АРОЕ - ɛ2, АРОЕ - ɛ3, АРОЕ - ɛ4 are detected.

EFFECT: method makes it possible to quickly obtain a noninvasively significant criterion for assessing the prognosis of the risk of developing a negative response to combined CT for patients with sporadic advanced ovarian cancer, which is a useful addition to the diagnostic complex for screening patients in the preoperative period and individualizes the approach to the treatment of patients with ovarian cancer.

1 cl, 4 dwg, 10 tbl, 3 ex

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RU 2 769 543 C2

Authors

Ivanova Tatiana Ilinichna

Krikunova Liudmila Ivanovna

Sychenkova Nataliia Ivanovna

Khorokhorina Vera Alekseevna

Shinkarkina Anna Petrovna

Murzaeva Alena Valerevna

Ivanov Sergei Anatolevich

Shegai Petr Viktorovich

Kaprin Andrei Dmitrievich

Dates

2022-04-01Published

2021-07-21Filed