FIELD: biotechnology.
SUBSTANCE: disclosed is an anti-LILRB1 antibody or an antigen-binding fragment thereof. Also disclosed are pharmaceutical compositions containing said antibodies for inhibiting immune evasion of tumor cells and treating oncological disease. Invention also relates to a nucleic acid coding an anti-LILRB1 antibody, a recombinant expression vector and a recombinant cell containing said nucleic acid, a method of producing an anti-LILRB1 antibody.
EFFECT: invention provides antibodies against LILRB1, having high specificity in relation to LILRB1.
12 cl, 5 dwg, 22 tbl, 6 ex
Title |
Year |
Author |
Number |
ANTI-LILRB1 ANTIBODY AND ITS USE |
2020 |
- Choi, Yoon Aa
- Kim, Jung A
- Jung, Saem
- Lee, Ji Hyun
- Na, Kyubong
- Kim, Yeonchul
- Kim, Han Byul
|
RU2801535C1 |
COMPOSITION FOR PREVENTION AND TREATMENT OF SKIN DISEASE CONTAINING SUBSTANCE SPECIFICALLY BINDING WITH VIMENTINE DERIVATIVE PEPTIDE |
2018 |
- Kim Yoon-Won
- Park Sungman
- Kim Min Soo
|
RU2751486C1 |
ANTI-HUMAN ANGIOPOIETIN-LIKE 4 PROTEIN ANTIBODIES |
2010 |
- Sliman U. Mark
- Gusarova Viktorija
- Kim Dzee Kh.
- Chen Gan
|
RU2580045C2 |
ANTIBODY FOR SPECIFIC BINDING TO N-TERMINAL DOMAIN OF LYSYL-TRNA SYNTHETASE EXPOSED ON EXTRACELLULAR MEMBRANE |
2019 |
- Kim Sunghoon
- Kwon Nam Hoon
|
RU2781304C1 |
PHARMACEUTICAL COMPOSITION CONTAINING AN ANTIBODY SPECIFICALLY BINDING WITH THE N-TERMINAL OF LYSYL-TRNA SYNTHETASE AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION OR TREATMENT OF DISEASES CAUSED BY CELL MIGRATION |
2018 |
- Kwon Nam Hoon
- Lee Jin Young
- Kim Sunghoon
|
RU2749591C1 |
FUSION PROTEIN COMPRISING IL-12 AND ANTI-FAP ANTIBODY, AND USE THEREOF |
2021 |
- Kim, Donggeon
- Ryu, Soomin
- Lee, Dahea
- Kim, Dongsu
- Chang, Jihoon
- Lee, Byoung Chul
|
RU2831612C1 |
ANTIBODY SPECIFICALLY BINDING TO ICAM-1 AND ITS USE |
2019 |
- Mun, Yu Ri
- Dzhi, Gil Jong
- Jun, Sangsun
- Kim, Dzhung Sik
|
RU2789757C2 |
C10orf54 ANTIBODIES AND USE THEREOF |
2015 |
- Lippinkott, Dzhon
- Van Der Khorst, Edvard Tejn, Khtun
- Kim, Sun, Yun
- Presta, Leonard, G.
- Tenissen, Yan-Villem
|
RU2714232C2 |
ANTI-C10orf54 ANTIBODIES AND APPLICATIONS THEREOF |
2015 |
- Lippinkott, Dzhon
- Van Der Khorst, Edvard Tejn, Khtun
- Kim, Sun, Yun
- Presta, Leonard, G.
- Tenissen, Yan-Villem
|
RU2819627C1 |
NEW O-SUCCINYL HOMOSERINE TRANSFERASE VARIANT AND METHOD FOR SYNTHESIS OF O-SUCCINYL HOMOSERINE USING SAID VARIANT |
2018 |
- Kim Kyungrim
- Shim Jihyun
- Kim Hyun Ah
- Shin Yong Uk
- Lee Peter
|
RU2747493C1 |